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|Matteo Berrettini advanced to the quarter-finals at a Grand Slam for the first time. (AFP/Mike Stobe)|
Berrettini, the 24th seed, eased to a 6-1, 6-4, 7-6 (8/6) win over Russia's 43rd-ranked Andrey Rublev to reach the last eight at a Grand Slam for the first time.
"It's something really crazy. I cannot believe it right now. I need a few hours to understand what happened," said Berrettini, 23, who goes on to play French 13th seed Gael Monfils or Spaniard Pablo Andujar.
"I'm just happy. Seeing my team and family here and crying, for me it's unbelievable."
Berrettini went one step further than his run to the last 16 at Wimbledon in July, where he was beaten by Roger Federer.
The Italian overcame a momentary lapse against Rublev as he dropped serve at 6-5 in the third set but sealed victory after two hours and 11 minutes in a tense tie-break.
"I think I did an unbelievable match. I thought Andrey was playing really good and playing with confidence," Berrettini said.
"I was mixing my tennis, using the slice, forehand and serve. I think all my weapons were really good today."